Мегаобучалка Главная | О нас | Обратная связь  


Text 5.2. Setting up a nerve impulse




Поможем в ✍️ написании учебной работы
Поможем с курсовой, контрольной, дипломной, рефератом, отчетом по практике, научно-исследовательской и любой другой работой

■ Essential targets:

By the end of this text you should be able to:

· explain how a resting potential is maintained

· explain how an action potential is generated.

Pre-reading

■ Discuss these questions with your partner. Then compare your ideas with the information given in the text.

1. What do you know about the nature of nerve impulses?

2. Why are nerve impulses important for humans?

 

■ Read the following text and make your essential assignments:

 

Investigating nerve impulses

Nerves convey information rapidly from one part of the body to another, enabling animals to respond quickly to changes in their external and internal environments. The information is carried in the form of electrical signals called nerve impulses.Most of our understanding of the nature of nerve impulses comes from work done on giant axons of squids. These are the nerve fibres responsible for the rapid escape movements of squids. Their large diameter (up to 1 mm) makes it possible to measure the electrical activity in a giant axon when it is at rest and when it is conveying a nerve impulse.

A fine glass microelectrode is inserted inside an axon, and the voltage (potential difference; p.d.) between it and a reference electrode on the surface of the axon can be displayed on a cathode ray oscilloscope. By convention, the potential difference of the inside of the cell is always measured relative to that on the outside, so that the outside potential is taken as zero.

Resting potential

A resting neurone is so called because it does not convey a nerve impulse, not because it is inactive. On the contrary, a resting neurone expends much energy in maintaining a potential difference across its membrane. This is called the resting potentialand measures about -70 millivolts.

During the resting potential, the inside of the neurone is negative relative to the outside because of an unequal distribution of charged ions. On the outside, sodium ions (Na+), chloride ions (Cl-), and calcium ions Ca2+) are present in higher concentrations than inside the cell. By contrast, the inside of the cell has a higher concentration of potassium ions (K+) and organic anions (negative ions).



This unequal distribution of ions results from a combination of active transport and diffusion of sodium and potassium ions across the cell membrane, and the inability of large organic anions to pass out of the cell. A sodium-potassium pumpactively transports sodium ions out of the neurone and potassium ions in. For every three sodium ions pumped out, only two potassium ions are pumped inwards. On its own, this would result in only a slight potential difference across the membrane. However, this difference is amplified by the membrane being about 50 times more permeable to potassium ions than to sodium ions. Potassium ions are able to diffuse freely back out of the cell down their concentration gradient, but the sodium ions diffuse back into the cell only very slowly. This creates a negative electrical charge inside compared with outside. Without active transport, an equilibrium would eventually be reached and there would be no potential difference across the membrane.

Action potential

A nerve impulse occurs when the resting potential across the membrane of a neurone has a sufficiently high stimulus. A stimulusis any disturbance in the external or internal environment which changes the potential difference across a membrane. The stimulus may be chemical, mechanical, thermal, or electrical, or it may be a change in light intensity.

The recording on the cathode ray oscilloscope shows the effects of a stimulus on a giant axon. When the stimulus is applied, the axon becomes depolarised;that is, the inside becomes temporarily less negative. If the stimulus is strong enough (if it exceeds the threshold level), an actionpotential occurs. There is a complete reversal of the charge across the nerve cell: the interior becomes positively charged relative to the outside. Typically, the action potential reaches a peak of about +35 millivolts. The potential difference then drops back down, undershoots the resting potential and finally returns to it. The return of the potential difference towards the resting potential is called repolarisation.The entire action potential takes about 7 milliseconds. Although this example refers specifically to a giant axon, its general features apply to all animal neurones.




Читайте также:
Генезис конфликтологии как науки в древней Греции: Для уяснения предыстории конфликтологии существенное значение имеет обращение к античной...
Как построить свою речь (словесное оформление): При подготовке публичного выступления перед оратором возникает вопрос, как лучше словесно оформить свою...
Почему двоичная система счисления так распространена?: Каждая цифра должна быть как-то представлена на физическом носителе...



©2015-2020 megaobuchalka.ru Все материалы представленные на сайте исключительно с целью ознакомления читателями и не преследуют коммерческих целей или нарушение авторских прав. (591)

Почему 1285321 студент выбрали МегаОбучалку...

Система поиска информации

Мобильная версия сайта

Удобная навигация

Нет шокирующей рекламы



(0.007 сек.)
Поможем в написании
> Курсовые, контрольные, дипломные и другие работы со скидкой до 25%
3 569 лучших специалисов, готовы оказать помощь 24/7